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2 . 2026

Cognitive functions after surgical interventions on extracranial carotid arteries (literature review)

Abstract

In recent years, surgical interventions on the carotid arteries – such as carotid endarterectomy and stenting – have become key methods for preventing ischemic stroke. In addition to their proven clinical effectiveness, increasing attention is being paid to their influence on patients’ cognitive functions.

This review summarizes current data from both domestic and international studies on the dynamics of cognitive function following carotid revascularization. It discusses the primary mechanisms behind cognitive changes, including reperfusion injury, microembolism, and cerebral hyperperfusion syndrome. Particular attention is given to the comparative evaluation of endarterectomy and stenting in terms of long-term cognitive outcomes.

The review also outlines key risk factors for cognitive impairment and proposes strategies to reduce them. The findings underscore the importance of an individualized approach when selecting surgical tactics and emphasize the need for further research in this area.

Keywords:cognitive functions; cognitive impairments; higher mental functions; carotid endarterectomy; transluminal balloon angioplasty; stenting; carotid artery; ischemic stroke; microembolism

For citation: Mkrtchyan A.N. Cognitive functions after surgical interventions on extracranial carotid arteries (literature review). Angiology and Vascular Surgery. Journal named after Academician A.V. Pokrovsky. 2026; 32 (2): 146–52. DOI: https://doi.org/10.33029/1027-6661-2026-32-2-146-152

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CHIEF EDITOR
CHIEF EDITOR
Yuri V. Belov
Academician of the Russian Academy of Sciences Doctor of Medical Sciences, Professor, President of the Russian Society of Angiologists and Vascular Surgeons

 

In accordance with the decision of the Presidium of the Russian Society of Angiologists and Vascular Surgeons, the journal "Angiology and Vascular Surgery" will be named after Academician A.V. Pokrovsky starting from No. 2/2022.

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