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3 . 2025

Neovasculgen® – has its effectiveness been proven? (Audiatur et altera pars)

Abstract

This work is controversial. It addresses only one question: is there a convincing evidence base at this stage of development on the positive effect of the already registered drug Neovasculgen® on the course of chronic lower limb ischemia in atherosclerotic lesions of the main vessels.

Conclusion. At the present stage, the evidence base on the benefits of using Neovasculgen® is insufficient to include this drug as a recommended therapeutic agent in the National Clinical Guidelines.

Keywords: chronic lower limb ischemia; angiogenesis; evidence base; stages of clinical trials

Funding. The study had no financial support.

Conflict of interest. The authors declare no conflicts of interest.

Authors’ contribution. Study conception and design – Vachev A.N., Bazylev V.V., Troitskiy A.V., Karpenko A.A.; data collection and handling – Vachev A.N., Bazylev V.V., Troitskiy A.V., Karpenko A.A.; draft manuscript preparation – Vachev A.N.; manuscript revision – Vachev A.N., Bazylev V.V., Troitskiy A.V., Karpenko A.A.

For citation: Vachev A.N., Bazylev V.V., Troitskiy A.V., Karpenko A.A. Neovasculgen® – has its effectiveness been proven? (Audiatur et altera pars). Angiology and Vascular Surgery. Journal named after Academician A.V. Pokrovsky. 2025; 31 (3): 16–9. DOI: https://doi.org/10.33029/1027-6661-2025-31-3-16-19

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CHIEF EDITOR
CHIEF EDITOR
Yuri V. Belov
Academician of the Russian Academy of Sciences Doctor of Medical Sciences, Professor, President of the Russian Society of Angiologists and Vascular Surgeons

 

In accordance with the decision of the Presidium of the Russian Society of Angiologists and Vascular Surgeons, the journal "Angiology and Vascular Surgery" will be named after Academician A.V. Pokrovsky starting from No. 2/2022.

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