Immediate results of balloon angioplasty for critical limb ischemia combined with coronavirus infection COVID-19

• Kuriyanov P.S.
• Zaichenko E.P.
• Zhukov D.V.
• Gusev A.A.
• Yakimova A.V.
• Bubnova N.A.
• Shatil M.A.
• Dobrydin O.N.
• Strizheletsky V.V.
• Chernyshev O.B.
• Andreev S.A.
• Taranenko M.Yu.
• Osadchiy A.A.
• Antiya A.E.

Abstract

The authors performed a single-group retrospective analysis of the results of endovascular interventions in a total of 8 patients suffering from critical limb ischemia with trophic changes on the foot and the novel coronavirus infection. The degree of pulmonary lesion according to the findings of computed tomography varied from 0.0% to 36.0% (median 25.0%). 87% were found to have infiltrative alterations by the type of polysegmental bilateral pneumonia (SpO₂ at rest amounted to not less than 95% without oxygen inhalation). Significant deviations in laboratory parameters were more often represented by anemia (8 of 8, 100%), lymphopenia (7 of 8, 87%). hypoalbuminemia (6 of 8, 75%), neutrophilic leukocytosis (5 of 8, 62%). Increased concentration of platelets was observed in only 2 patients of 8 (25.0%). The estimated value of predicted perioperative lethality according to the ACS NSQIP scale varied from 0.8 to 4.0%. In the remote period, we assessed overall survival, limb salvage rate and healing of trophic defects on the foot.

Revascularization was always technically successful. There were no intraoperative complications in the studied group. Early postoperative mortality amounted to 13% (n=1). The duration of postoperative follow up was form 1 to 8 months (median 5 months).

Overall survival amounted to 87%, limb salvage rate to 100%, freedom from repeat revascularization to 85%, rate of trophic defect healing to 43%.

Conclusion. Balloon angioplasty on lower-limb arteries in chronic limb critical ischemia and a combination with novel coronavirus infection was effective in patients with a non-severe course of coronavirus infection. Additional comparative studies are warranted for more accurate prediction of immediate and remote outcomes of interventions in this difficult cohort of patients.

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

For citation: Kuriyanov P.S., Zaichenko E.P., Zhukov D.V., Gusev A.A., Yakimova A.V., Bubnova N.A., Shatil M.A., Dobrydin O.N., Strizheletsky V.V., Chernyshev O.B., Andreev S.A., Taranenko M.Yu., Osadchiy A.A., Antiya A.E. Immediate results of balloon angioplasty for critical limb ischemia combined with coronavirus infection COVID-19. Angiology and Vascular Surgery. 2022; 28 (1): 72–9. DOI: https://doi.org/10.33029/1027-6661-2022-28-1-72-79 (in Russian)

Keywords:chronic limb-threatening ischemia; novel coronavirus infection; endovascular interventions; balloon angioplasty; multilevel lesions

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